9 insiders reported 86 Form 4 transactions for Spyre Therapeutics, Inc. (SYRE) over the past 18 months (most recent 2026-08-10). Recent activity: Albers Jeffrey W. (Director) Buy 5,000 shares, Albers Jeffrey W. (Director) Sell 5,000 shares, Albers Jeffrey W. (Director) Sell 8,000 shares, Albers Jeffrey W. (Director) Sell 10,000 shares, Turtle Cameron (Chief Executive Officer) Sell 800 shares. Source: SEC Form 4.
| Date | Insider | Title | Type | Shares | Value |
|---|---|---|---|---|---|
| 2026-08-10 | Albers Jeffrey W. | Director | Buy | 5,000 | $51,950 |
| 2026-08-10 | Albers Jeffrey W. | Director | Sell | 5,000 | $522,350 |
| 2026-08-10 | Albers Jeffrey W. | Director | Sell | 8,000 | $835,040 |
| 2026-08-10 | Albers Jeffrey W. | Director | Sell | 10,000 | $1.0M |
| 2026-08-05 | Turtle Cameron | Chief Executive Officer | Sell | 800 | $75,176 |
| 2026-08-05 | Burrows Scott L | Chief Financial Officer | Buy | 7,500 | $108,750 |
| 2026-08-05 | Turtle Cameron | Chief Executive Officer | Sell | 7,157 | $680,631 |
| 2026-08-05 | Burrows Scott L | Chief Financial Officer | Sell | 5,100 | $485,571 |
| 2026-08-05 | Turtle Cameron | Chief Executive Officer | Sell | 5,635 | $540,566 |
| 2026-08-05 | Burrows Scott L | Chief Financial Officer | Sell | 2,300 | $221,490 |
| 2026-08-05 | Turtle Cameron | Chief Executive Officer | Sell | 1,392 | $134,773 |
| 2026-08-05 | Burrows Scott L | Chief Financial Officer | Sell | 100 | $9,710 |
| 2026-08-05 | Turtle Cameron | Chief Executive Officer | Sell | 16 | $1,559 |
| 2026-07-02 | Turtle Cameron | Chief Executive Officer | Sell | 4,234 | $373,100 |
| 2026-07-02 | Burrows Scott L | Chief Financial Officer | Buy | 7,500 | $108,750 |
| 2026-07-02 | Sloan Sheldon | Chief Medical Officer | Buy | 8,334 | $228,852 |
| 2026-07-02 | Turtle Cameron | Chief Executive Officer | Sell | 10,176 | $889,789 |
| 2026-07-02 | Burrows Scott L | Chief Financial Officer | Sell | 5,775 | $505,601 |
| 2026-07-02 | Sloan Sheldon | Chief Medical Officer | Sell | 6,500 | $568,880 |
| 2026-07-02 | Turtle Cameron | Chief Executive Officer | Sell | 590 | $52,457 |
| 2026-07-02 | Burrows Scott L | Chief Financial Officer | Sell | 1,725 | $152,438 |
| 2026-07-02 | Sloan Sheldon | Chief Medical Officer | Sell | 1,834 | $162,016 |
| 2026-06-26 | Burrows Scott L | Chief Financial Officer | Buy | 15,000 | $217,500 |
| 2026-06-26 | Burrows Scott L | Chief Financial Officer | Sell | 5,000 | $435,600 |
| 2026-06-26 | Burrows Scott L | Chief Financial Officer | Sell | 10,000 | $871,400 |
Source: SEC Form 4 filings · as of 2026-08-10