| 1 | BlackRock, Inc. | $210.7M | 20.7M | Added |
| 2 | VANGUARD GROUP INC | $192.5M | 18.9M | Added |
| 3 | ARCH Venture Management, LLC | $129.4M | 12.7M | Trimmed |
| 4 | SB INVESTMENT ADVISERS (UK) LTD | $111.6M | 10.9M | Hold |
| 5 | STATE STREET CORP | $101.5M | 10.0M | Added |
| 6 | GSK plc | $87.1M | 8.6M | Hold |
| 7 | Point72 Asset Management, L.P. | $57.7M | 5.7M | Added |
| 8 | GEODE CAPITAL MANAGEMENT, LLC | $34.1M | 3.3M | Added |
| 9 | DIMENSIONAL FUND ADVISORS LP | $31.8M | 3.1M | Added |
| 10 | ADAR1 Capital Management, LLC | $25.0M | 2.5M | Trimmed |
| 11 | GOLDMAN SACHS GROUP INC | $24.1M | 2.4M | Trimmed |
| 12 | FMR LLC | $23.6M | 2.3M | Added |
| 13 | MORGAN STANLEY | $22.5M | 2.2M | Trimmed |
| 14 | Nuveen, LLC | $20.2M | 2.0M | Added |
| 15 | Pictet Asset Management Holding SA | $19.9M | 2.0M | Added |
| 16 | Boxer Capital Management, LLC | $19.0M | 1.9M | Hold |
| 17 | NORTHERN TRUST CORP | $14.6M | 1.4M | Added |
| 18 | Hudson Bay Capital Management LP | $13.9M | 1.4M | Trimmed |
| 19 | GordonMD Global Investments LP | $13.8M | 1.4M | Trimmed |
| 20 | Sixth Street Partners Management Company, L.P. | $13.5M | 1.3M | New |
| 21 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $13.5M | 1.3M | Added |
| 22 | BANK OF AMERICA CORP /DE/ | $11.6M | 1.1M | Added |
| 23 | TWO SIGMA INVESTMENTS, LP | $11.3M | 1.1M | Trimmed |
| 24 | Sio Capital Management, LLC | $11.0M | 1.1M | Trimmed |
| 25 | CITADEL ADVISORS LLC | $10.6M | 1.0M | Trimmed |