| 1 | Jupiter Topco LLC | $17.9M | 4.7M | New |
| 2 | BlackRock, Inc. | $14.0M | 3.7M | Added |
| 3 | VANGUARD GROUP INC | $12.0M | 3.1M | Added |
| 4 | MILLENNIUM MANAGEMENT LLC | $11.8M | 3.1M | Added |
| 5 | Velan Capital Investment Management LP | $10.9M | 2.8M | Added |
| 6 | Blackstone Inc. | $8.7M | 2.3M | Hold |
| 7 | ORBIMED ADVISORS LLC | $8.5M | 2.2M | New |
| 8 | Sio Capital Management, LLC | $7.3M | 1.9M | Trimmed |
| 9 | ACORN CAPITAL ADVISORS, LLC | $6.7M | 1.8M | Hold |
| 10 | Integral Health Asset Management, LLC | $5.7M | 1.5M | Trimmed |
| 11 | 5AM Venture Management, LLC | $5.2M | 1.4M | Hold |
| 12 | GEODE CAPITAL MANAGEMENT, LLC | $5.1M | 1.3M | Added |
| 13 | CITADEL ADVISORS LLC | $4.7M | 1.2M | Trimmed |
| 14 | STATE STREET CORP | $4.1M | 1.1M | Added |
| 15 | Qube Research & Technologies Ltd | $4.0M | 1.0M | Added |
| 16 | Balyasny Asset Management L.P. | $3.9M | 1.0M | New |
| 17 | BAKER BROS. ADVISORS LP | $3.7M | 971,614 | Hold |
| 18 | ADAR1 Capital Management, LLC | $3.6M | 940,512 | Hold |
| 19 | BANK OF AMERICA CORP /DE/ | $3.4M | 882,179 | Trimmed |
| 20 | MARSHALL WACE, LLP | $2.7M | 701,021 | Added |
| 21 | DIMENSIONAL FUND ADVISORS LP | $2.6M | 683,230 | Added |
| 22 | NORTHERN TRUST CORP | $2.1M | 552,306 | Added |
| 23 | Point72 Asset Management, L.P. | $2.1M | 548,932 | Trimmed |
| 24 | GOLDMAN SACHS GROUP INC | $2.1M | 546,227 | Added |
| 25 | Catalio Capital Management, LP | $2.0M | 520,148 | Trimmed |