52 institutions reported holding $816.0M of SEAPORT THERAPEUTICS (SPTX) in SEC 13F filings for 2026-06-30. Largest institutional holders: ARCH Venture Management, LLC ($136.6M), GENERAL ATLANTIC, L.P. ($132.5M), Sofinnova Investments, Inc. ($77.4M), GOLDMAN SACHS GROUP INC ($47.3M), TRV GP VI, LLC ($44.8M). Source: SEC Form 13F.
| Rank | Institution | Value | Shares | Change |
|---|---|---|---|---|
| 1 | ARCH Venture Management, LLC | $136.6M | 6.3M | New |
| 2 | GENERAL ATLANTIC, L.P. | $132.5M | 6.1M | New |
| 3 | Sofinnova Investments, Inc. | $77.4M | 3.6M | New |
| 4 | GOLDMAN SACHS GROUP INC | $47.3M | 2.2M | New |
| 5 | TRV GP VI, LLC | $44.8M | 2.1M | New |
| 6 | CANADA PENSION PLAN INVESTMENT BOARD | $42.9M | 2.0M | New |
| 7 | JPMORGAN CHASE & CO | $40.9M | 1.8M | New |
| 8 | Foresite Capital Management VI LLC | $38.7M | 1.8M | New |
| 9 | PRICE T ROWE ASSOCIATES INC /MD/ | $28.4M | 1.3M | New |
| 10 | FMR LLC | $25.7M | 1.2M | New |
| 11 | Bellevue Group AG | $23.9M | 1.1M | New |
| 12 | Siren, L.L.C. | $23.8M | 1.1M | New |
| 13 | JENNISON ASSOCIATES LLC | $23.5M | 1.1M | New |
| 14 | VANGUARD GROUP INC | $15.3M | 703,229 | New |
| 15 | RA CAPITAL MANAGEMENT, L.P. | $15.2M | 700,000 | New |
| 16 | Woodline Partners LP | $12.7M | 586,345 | New |
| 17 | PERCEPTIVE ADVISORS LLC | $10.9M | 500,000 | New |
| 18 | BRAIDWELL LP | $10.9M | 500,000 | New |
| 19 | PRINCIPAL FINANCIAL GROUP INC | $9.0M | 414,672 | New |
| 20 | Aberdeen Group plc | $6.7M | 310,355 | New |
| 21 | UBS Group AG | $6.1M | 279,184 | New |
| 22 | BlackRock, Inc. | $5.0M | 229,863 | New |
| 23 | SEVEN GRAND MANAGERS, LLC | $4.9M | 225,000 | New |
| 24 | CITADEL ADVISORS LLC | $4.2M | 191,144 | New |
| 25 | GEODE CAPITAL MANAGEMENT, LLC | $3.8M | 175,866 | New |
Source: SEC Form 13F filings · as of 2026-06-30