| 1 | ADAGE CAPITAL PARTNERS GP, L.L.C. | $16.8M | 9.0M | Added |
| 2 | Aberdeen Group plc | $16.6M | 8.9M | Added |
| 3 | Affinity Asset Advisors, LLC | $10.3M | 5.5M | Added |
| 4 | Privium Fund Management B.V. | $10.3M | 5.5M | Added |
| 5 | Ikarian Capital, LLC | $6.4M | 3.4M | Added |
| 6 | Woodline Partners LP | $6.1M | 3.3M | New |
| 7 | HEIGHTS CAPITAL MANAGEMENT, INC | $5.1M | 2.8M | New |
| 8 | MORGAN STANLEY | $3.3M | 1.8M | Added |
| 9 | SPHERA FUNDS MANAGEMENT LTD. | $3.3M | 1.8M | New |
| 10 | Kynam Capital Management, LP | $2.9M | 1.6M | Hold |
| 11 | DAFNA Capital Management LLC | $2.8M | 1.5M | Trimmed |
| 12 | Squadron Capital Management LLC | $2.8M | 1.5M | New |
| 13 | 683 Capital Management, LLC | $2.6M | 1.4M | New |
| 14 | CITADEL ADVISORS LLC | $2.2M | 1.2M | Added |
| 15 | PLATINUM INVESTMENT MANAGEMENT LTD | $2.2M | 1.2M | Trimmed |
| 16 | TWO SIGMA INVESTMENTS, LP | $2.1M | 1.1M | Added |
| 17 | Eversept Partners, LP | $1.9M | 1.0M | New |
| 18 | BOOTHBAY FUND MANAGEMENT, LLC | $1.8M | 948,736 | Added |
| 19 | DIADEMA PARTNERS LP | $1.7M | 926,016 | Added |
| 20 | UBS Group AG | $1.2M | 639,243 | Added |
| 21 | NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | $1.2M | 620,000 | Hold |
| 22 | M28 Capital Management LP | $1.1M | 599,793 | Hold |
| 23 | RAYMOND JAMES FINANCIAL INC | $1.1M | 571,073 | Added |
| 24 | Lynx1 Capital Management LP | $969,828 | 521,413 | Added |
| 25 | JANE STREET GROUP, LLC | $846,493 | 455,104 | Added |