| 1 | SUVRETTA CAPITAL MANAGEMENT, LLC | $154.5M | 11.5M | Hold |
| 2 | Jupiter Topco LLC | $33.1M | 2.5M | New |
| 3 | FRANKLIN RESOURCES INC | $32.3M | 2.4M | Added |
| 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | $28.4M | 2.1M | Hold |
| 5 | RA CAPITAL MANAGEMENT, L.P. | $24.8M | 1.9M | Hold |
| 6 | Nantahala Capital Management, LLC | $19.9M | 1.5M | Added |
| 7 | BlackRock, Inc. | $18.8M | 1.4M | Added |
| 8 | VANGUARD GROUP INC | $17.0M | 1.3M | Added |
| 9 | Simplify Asset Management Inc. | $13.5M | 1.0M | Added |
| 10 | INFINITUM ASSET MANAGEMENT, LLC | $12.3M | 923,006 | Hold |
| 11 | MILLENNIUM MANAGEMENT LLC | $12.3M | 921,299 | Added |
| 12 | Alyeska Investment Group, L.P. | $10.0M | 750,000 | Hold |
| 13 | SILVERARC CAPITAL MANAGEMENT, LLC | $9.1M | 679,826 | Trimmed |
| 14 | Balyasny Asset Management L.P. | $8.7M | 650,503 | Trimmed |
| 15 | GEODE CAPITAL MANAGEMENT, LLC | $8.2M | 611,736 | Added |
| 16 | AMERIPRISE FINANCIAL INC | $5.4M | 401,245 | Trimmed |
| 17 | STATE STREET CORP | $5.1M | 377,973 | Added |
| 18 | MYDA Advisors LLC | $3.3M | 250,000 | Added |
| 19 | Schonfeld Strategic Advisors LLC | $3.1M | 235,357 | Added |
| 20 | AWM Investment Company, Inc. | $2.5M | 187,977 | Hold |
| 21 | NORTHERN TRUST CORP | $2.4M | 178,434 | Added |
| 22 | GOLDMAN SACHS GROUP INC | $2.4M | 178,041 | Trimmed |
| 23 | Burkehill Global Management, LP | $2.0M | 150,000 | Hold |
| 24 | Russell Investments Group, Ltd. | $1.7M | 128,970 | Added |
| 25 | UBS Group AG | $1.7M | 125,431 | Added |