Opaleye Management Inc. (CIK 1595855) reported 181 SEC Form 4 insider transactions across 7 companies over the past 18 months (most recent 2026-08-19). Recent activity: Buy GRCE (11,608 shares), Buy SLGL (951 shares), Buy ACOG (2,900 shares), Buy ACOG (50,000 shares), Buy ACOG (130 shares). Source: SEC Form 4.
| Date | Company | Role | Type | Shares | Value |
|---|---|---|---|---|---|
| 2026-08-19 | Grace Therapeutics, Inc. (GRCE) | 10% Owner | Buy | 11,608 | $24,206 |
| 2026-08-14 | Sol-Gel Technologies Ltd. (SLGL) | 10% Owner | Buy | 951 | $67,996 |
| 2026-08-04 | Alpha Cognition Inc. (ACOG) | 10% Owner | Buy | 2,900 | $22,976 |
| 2026-08-04 | Alpha Cognition Inc. (ACOG) | 10% Owner | Buy | 50,000 | $400,000 |
| 2026-07-28 | Alpha Cognition Inc. (ACOG) | 10% Owner | Buy | 130 | $1,027 |
| 2026-07-24 | Alpha Cognition Inc. (ACOG) | 10% Owner | Buy | 140,237 | $1.1M |
| 2026-07-24 | Alpha Cognition Inc. (ACOG) | 10% Owner | Buy | 10,000 | $78,337 |
| 2026-07-24 | Alpha Cognition Inc. (ACOG) | 10% Owner | Buy | 49,849 | $388,588 |
| 2026-07-17 | Eton Pharmaceuticals, Inc. (ETON) | 10% Owner | Sell | 15,000 | $563,146 |
| 2026-07-17 | Eton Pharmaceuticals, Inc. (ETON) | 10% Owner | Sell | 13,315 | $499,886 |
| 2026-07-16 | Eton Pharmaceuticals, Inc. (ETON) | 10% Owner | Sell | 15,000 | $563,146 |
| 2026-07-16 | Eton Pharmaceuticals, Inc. (ETON) | 10% Owner | Sell | 13,315 | $499,886 |
| 2026-07-15 | Sol-Gel Technologies Ltd. (SLGL) | 10% Owner | Buy | 775 | $57,263 |
| 2026-07-15 | Sol-Gel Technologies Ltd. (SLGL) | 10% Owner | Buy | 920 | $67,556 |
| 2026-07-10 | Sol-Gel Technologies Ltd. (SLGL) | 10% Owner | Buy | 300 | $22,107 |
| 2026-07-10 | Sol-Gel Technologies Ltd. (SLGL) | 10% Owner | Buy | 229 | $16,935 |
| 2026-07-07 | Eton Pharmaceuticals, Inc. (ETON) | 10% Owner | Sell | 65,000 | $2.4M |
| 2026-07-07 | Eton Pharmaceuticals, Inc. (ETON) | 10% Owner | Sell | 25,000 | $934,628 |
| 2026-07-07 | Eton Pharmaceuticals, Inc. (ETON) | 10% Owner | Sell | 10,000 | $380,000 |
| 2026-07-07 | Eton Pharmaceuticals, Inc. (ETON) | 10% Owner | Sell | 20,000 | $767,456 |
| 2026-07-07 | Eton Pharmaceuticals, Inc. (ETON) | 10% Owner | Sell | 6,685 | $256,522 |
| 2026-07-02 | Sol-Gel Technologies Ltd. (SLGL) | 10% Owner | Buy | 312 | $22,461 |
| 2026-07-02 | Sol-Gel Technologies Ltd. (SLGL) | 10% Owner | Buy | 1,400 | $100,759 |
| 2026-06-29 | Alpha Cognition Inc. (ACOG) | 10% Owner | Buy | 197 | $1,280 |
| 2026-06-29 | Alpha Cognition Inc. (ACOG) | 10% Owner | Buy | 152,336 | $975,209 |
Source: SEC Form 4 filings · as of 2026-08-19